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Forigerimod

CD4 T-cell Modulator

Forigerimod is a CD4 T-cell modulator that functions by inhibiting autophagy through its active peptide fragment derived from U1 small nuclear ribonucleoprotein 70 kDa, which is phosphorylated at Ser140. This compound is particularly valuable in the investigation of autoimmune disorders, including systemic lupus erythematosus (SLE), due to its ability to modulate T-cell responses. Researchers may utilize Forigerimod to explore therapeutic strategies targeting dysregulated immune responses in various autoimmune conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Modulator
CAS Number	497156-60-2
Applications	CD4 T-cell Modulator
Formula	C₁₁₇H₁₈₁N₃₄O₃₂PS
Molecular Weight	2638.94
Synonyms	IPP-201101
SMILES	CC[C@H](C)[C@H](NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](COP(O)(O)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.