Fig. 1 · Structure
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Forphenicine
Alkaline Phosphatase Inhibitor
Forphenicine is a potent inhibitor of alkaline phosphatase, derived from the bacterial metabolite found in Sphingomonas fulvoviridis. This compound demonstrates significant cytotoxicity against HL-60 leukemia cells at a concentration of 10 µM. Additionally, Forphenicine has shown the ability to enhance survival rates in a guinea pig model of experimental autoimmune encephalomyelitis (EAE), making it a valuable tool for research in cancer and autoimmune diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 57784-96-0 |
| Applications | Alkaline Phosphatase Inhibitor |
| Formula | C9H9NO4 |
| Molecular Weight | 195.17 |
| SMILES | OC([C@H](C1=CC(O)=C(C=C1)C=O)N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.