Fig. 1 · Structure
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Fosinopril
ACE Inhibitor
Fosinopril is a potent angiotensin-converting enzyme (ACE) inhibitor characterized by a non-competitive inhibition mechanism. It has an IC50 value of 0.18 μM and a Ki value of 1.675 μM, demonstrating effective suppression of ACE activity. Fosinopril is commonly used in research related to hypertension and cardiovascular health, facilitating the study of blood pressure regulation and related pharmacological effects.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 98048-97-6 |
| Applications | ACE Inhibitor |
| Formula | C30H46NO7P |
| Molecular Weight | 563.66 |
| Synonyms | SQ28555 free acid |
| SMILES | O=C(O)[C@H]1N(C(C[P@@](CCCCC2=CC=CC=C2)(O[C@H](OC(CC)=O)C(C)C)=O)=O)C[C@H](C3CCCCC3)C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.