FOSL1 degrader 1

Name: FOSL1 degrader 1
Brand: Adooq Bioscience
SKU: A23949
Rating: 5 (288 reviews)

Catalog No.: A23949

FOSL1 degrader

FOSL1 Degrader 1 (4) is a potent T-5224-based PROTAC that selectively degrades FOSL1 (AP-1), suppressing cancer stemness gene expression in head and neck squamous cell carcinoma (HNSCC). It effectively inhibits tumor growth and eliminates cancer stem cells, showing 30–100 times greater efficacy than T-5224.

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Grouped product items
Size	Price	Stock
5mg	$675.00	In stock
10mg	$1,163.00	In stock
50mg	$3,450.00	In stock
100mg	$6,750.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description	FOSL1 Degrader 1 (4) is a potent T-5224-based PROTAC that selectively degrades FOSL1 (AP-1), suppressing cancer stemness gene expression in head and neck squamous cell carcinoma (HNSCC). It effectively inhibits tumor growth and eliminates cancer stem cells, showing 30–100 times greater efficacy than T-5224.

Product Information

Catalog Num	A23949
Formula	C58H69N5O18
Molecular Weight	1124.19
CAS Number	nan
SMILES	O=C1CCC(N2C(C(C(NCCOCCOCCOCCOCCOCCOCCOCCNC(CCC3=C(OCC4=CC(ON=C5O)=C5C=C4)C=CC(C(C6=C(O)C=C(OC7CCCC7)C=C6)=O)=C3)=O)=CC=C8)=C8C2=O)=O)C(N1)=O
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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