Fig. 1 · Structure
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FOXM1-IN-1
FOXM1 Inhibitor
FOXM1-IN-1 is a potent inhibitor of the transcription factor FOXM1, exhibiting an IC50 of 2.65 µM. This compound demonstrates significant antiproliferative activity and effectively reduces the expression levels of FOXM1, as well as associated proteins PLK1 and CDC25B. FOXM1-IN-1 is suitable for use in research applications targeting cell proliferation and cancer biology, contributing valuable insights into the modulation of FOXM1-related pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2864407-22-5 |
| Applications | FOXM1 Inhibitor |
| Formula | C23H30ClNO3 |
| Molecular Weight | 403.94 |
| SMILES | ClC1=CC=C(C=C1)COC2=CC=C(C=C2)OCCOCCNC3CCCCC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.