Fig. 1 · Structure
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FPL64176
L-type Ca2+ Channels Agonist
FPL64176 is a potent agonist of L-type Ca2+ channels, exhibiting an EC50 value of 16 nM. This nondihydropyridine compound significantly enhances calcium influx, making it valuable for studies on cardiac and smooth muscle contractility. Its specific action on L-type Ca2+ channels renders it an effective tool for investigating calcium-dependent cellular processes and therapeutic targets in cardiovascular research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 120934-96-5 |
| Applications | L-type Ca2+ Channels Agonist |
| Formula | C22H21NO3 |
| Molecular Weight | 347.41 |
| SMILES | O=C(C1=C(C)NC(C)=C1C(C2=CC=CC=C2CC3=CC=CC=C3)=O)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.