Fig. 1 · Structure

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FR 75513

Biochemical Assay Reagent

FR 75513 is a 1,1'-biphenyl-2,6-dicarboxylic acid diester compound known for its ability to inhibit detrusor muscle contraction. It demonstrates significant pharmacological activity, with an IC50 of 3.3 μg/mL in guinea pig bladder assays and an ID50 of 0.04 mg/kg following intravenous administration in anesthetized rats. This compound is valuable for research applications in urology and muscle contraction studies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 127975-78-4
Applications Biochemical Assay Reagent
Formula C19H19NO7
Molecular Weight 373.36
SMILES
O=C(C1=C(C=C(C)C(C(OC(C)C)=O)=C1C2=C([N+]([O-])=O)C=CC=C2)O)OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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