Fig. 1 · Structure
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FR054
PGM3 Inhibitor
FR054 is a selective inhibitor of the enzyme phosphoglucomutase 3 (PGM3), targeting the hexosamine biosynthetic pathway. It demonstrates significant anti-breast cancer activity by disrupting cellular metabolism and promoting apoptotic pathways. This reagent is valuable for research applications focusing on cancer metabolism, therapeutic development, and understanding the role of glycosylation in tumor biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 35954-65-5 |
| Applications | PGM3 Inhibitor |
| Formula | C14H19NO8 |
| Molecular Weight | 329.30 |
| SMILES | CC(O[C@@H]1[C@]2([H])[C@](OC(C)=N2)([H])O[C@@H]([C@H]1OC(C)=O)COC(C)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.