Fig. 1 · Structure
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FR221647
Adenosine Deaminase Inhibitor
FR221647 is an orally active non-nucleoside inhibitor of adenosine deaminase, specifically targeting the enzyme responsible for the hydrolytic deamination of adenosine. This compound demonstrates a selective inhibitory effect without cytotoxicity at concentrations of 100 μM. It is valuable for research applications related to adenosine signaling and purinergic pathways, providing insights into various physiological and pathological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 256461-28-6 |
| Applications | Adenosine Deaminase Inhibitor |
| Formula | C14H17N3O2 |
| Molecular Weight | 259.30 |
| SMILES | O=C(C1=CN(C(CO)CCC2=CC=CC=C2)C=N1)N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.