Fig. 1 · Structure
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Frataxin-IN-1
Frataxin Inhibitor
Frataxin-IN-1 is a selective Frataxin inhibitor with an IC50 value of 45 μM. This compound is valuable for investigating the pathophysiology of Friedreich's ataxia (FRDA) and the role of Frataxin in mitochondrial function. Its study may provide insights into potential therapeutic strategies for neurodegenerative disorders associated with Frataxin deficiency.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 102616-64-8 |
| Applications | Frataxin Inhibitor |
| Formula | C20H23NO6 |
| Molecular Weight | 373.40 |
| SMILES | COC1=CC=CC(=C1OC)C(C2=CC3=C(C=C2O)OCO3)N4CCOCC4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.