Fig. 1 · Structure
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Fraxinol
Cytochrome P450 Inhibitor
Fraxinol is a potent inhibitor of cytochrome P450 enzymes, primarily investigated for its role in drug metabolism and biotransformation. This compound, isolated from Lobelia chinensis, has demonstrated significant biological activity, making it relevant in studies focusing on pharmacokinetics and potential drug interactions. Fraxinol can be utilized in research aimed at understanding the metabolic pathways and toxicity profiles of various pharmaceuticals.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 486-28-2 |
| Applications | Cytochrome P450 Inhibitor |
| Formula | C11H10O5 |
| Molecular Weight | 222.19 |
| SMILES | O=C1C=CC2=C(OC)C(O)=C(OC)C=C2O1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.