Fig. 1 · Structure
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Fructose-arginine
AIM2 Inhibitor
Fructose-arginine is an inhibitor of the AIM2 inflammasome. It effectively reduces the secretion of pro-inflammatory cytokines IL-1β and IL-18, as well as inhibits caspase-1 activation, Asc pyroptosome formation, and Gsdmd cleavage associated with AIM2 activity. This compound is valuable for research focused on inflammasome signaling pathways and their roles in various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 25020-14-8 |
| Applications | AIM2 Inhibitor |
| Formula | C12H24N4O7 |
| Molecular Weight | 336.34 |
| SMILES | OC[C@@H](O)[C@@H](O)[C@H](O)C(CN[C@H](C(O)=O)CCCNC(N)=N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.