Fig. 1 · Structure
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Fructose-phenylalanine
ACE Inhibitor
Fructose-phenylalanine is a non-competitive angiotensin-converting enzyme (ACE) inhibitor that exhibits an IC50 of 0.19 mM. By forming a stable complex with Zn2+ ions at the active site of ACE, it effectively blocks the conversion of angiotensin I to angiotensin II, leading to reduced blood pressure. This compound is of significant interest for studying cardiovascular diseases and exploring therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 31105-03-0 |
| Applications | ACE Inhibitor |
| Formula | C15H21NO7 |
| Molecular Weight | 327.33 |
| Synonyms | Fru-Phe |
| SMILES | OC[C@@H](O)[C@@H](O)[C@H](O)C(CN[C@H](C(O)=O)CC1=CC=CC=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.