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FASN inhibitor
In Stock
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| Cell Line | Activity | Value | Description | Reference |
|---|---|---|---|---|
| MV4-11 | IC50 | 0.026 μM | Antiproliferative activity against human MV4-11 cells after 96 hrs by CellTiter-Glo reagent-based assay | [PMID: 30803804] |
| PC-3 | IC50 | 0.047 μM | Antiproliferative activity against human PC3 cells after 96 hrs by MTT assay | [PMID: 30803804] |
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1630808-89-7 |
| Applications | FASN inhibitor |
| Formula | C22H20FN3O4 |
| Molecular Weight | 409.41 |
| SMILES | O=C(C1(CC1)O)N2CCN(C(C3=CC=C(C4=NC5=C(C=C(F)C=C5)O4)C=C3)=O)CC2 |
| Solvent | Reported Solubility |
|---|---|
| DMSO | 25 mg/mL (61.06 mM) |
| Water | Insoluble |
| Ethanol | 3 mg/mL (7.32 mM) |
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
