Fig. 1 · Structure
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FTO-IN-1
FTO Inhibitor
FTO-IN-1 is a potent inhibitor of the fat mass and obesity-associated enzyme (FTO), demonstrating an IC50 of less than 1 μM. This compound is instrumental for investigating the role of FTO in cancer research, particularly in the context of metabolic regulation and adipocyte biology. Its inhibitory effects on FTO provide valuable insights into the pathways associated with obesity and related malignancies, making it a critical tool for biochemical studies in these areas.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2243944-92-3 |
| Applications | FTO Inhibitor |
| Formula | C18H16Cl2N4O2 |
| Molecular Weight | 391.25 |
| SMILES | O=C(NO)C1=CC=CC=C1NC2=C(Cl)C=C(C3=C(C)NN=C3C)C=C2Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.