Fig. 1 · Structure

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FTO-IN-13

FTO Inhibitor

FTO-IN-13 is a potent inhibitor of the fat mass and obesity-associated protein (FTO), exhibiting significant antiproliferative activity. This compound induces apoptosis in cancer cells by downregulating the expression of the anti-apoptotic protein Bcl-2 and increasing active Caspase 3 levels. Additionally, FTO-IN-13 reduces the expression of oncogenes MYC and CEBPA, highlighting its potential as an effective agent in cancer research and therapeutic applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 687600-25-5
Applications FTO Inhibitor
Formula C18H12Br2N2O4
Molecular Weight 480.11
SMILES
O=C(C1=CC2=C(C=C1O)C=CC=C2)N/N=C/C3=CC(Br)=C(C(Br)=C3O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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