Fig. 1 · Structure
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FTO-IN-3
FTO Inhibitor
FTO-IN-3 is a selective inhibitor of fat mass and obesity-associated protein (FTO), which plays a critical role in the regulation of RNA methylation and metabolism. This compound has been shown to impair self-renewal in glioblastoma stem cells, making it a valuable tool for investigating stem cell biology and therapeutic strategies in glioblastoma. Its application in research could provide insights into the modulation of cancer stem cell properties and the potential development of targeted therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2585198-87-2 |
| Applications | FTO Inhibitor |
| Formula | C12H10N4OS |
| Molecular Weight | 258.30 |
| SMILES | NC1=NC2=CC=C(C3=CN=C(OC)N=C3)C=C2S1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.