Fig. 1 · Structure
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FTO-IN-7
FTO Inhibitor
FTO-IN-7 is a selective inhibitor of FTO (fat mass and obesity-associated protein) with an IC50 of less than 1 μM. It demonstrates significant biological activity in the modulation of obesity-related pathways and has been utilized in research focused on small-cell lung cancer and human bone marrow striated muscle cancer. This compound is valuable for studies investigating the role of FTO in cancer biology and metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2243736-37-8 |
| Applications | FTO Inhibitor |
| Formula | C18H15Cl2N3O2 |
| Molecular Weight | 376.24 |
| SMILES | O=C(C1=C(NC2=C(C=C(C3=C(C)NN=C3C)C=C2Cl)Cl)C=CC=C1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.