Fig. 1 · Structure
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Fumitremorgin C
ABCG2/BRCP Inhibitor
Fumitremorgin C is a selective inhibitor of the ATP-binding cassette transporter G2 (ABCG2), also known as breast cancer resistance protein (BCRP). This compound demonstrates significant activity in modulating drug resistance in cancer cells by inhibiting the efflux of chemotherapeutic agents. Fumitremorgin C is valuable in research focused on cancer pharmacology and the study of multidrug resistance mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 118974-02-0 |
| Applications | ABCG2/BRCP Inhibitor |
| Formula | C22H25N3O3 |
| Molecular Weight | 379.45 |
| Synonyms | 12α-Fumitremorgin C |
| SMILES | O=C([C@]1([H])CC2=C([C@H](/C=C(C)\C)N13)NC4=C2C=CC(OC)=C4)N5[C@](CCC5)([H])C3=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.