Fig. 1 · Structure
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Furosemide sodium
NKCC Inhibitor
Furosemide sodium is a potent inhibitor of the Na+/K+/2Cl- cotransporter (NKCC), specifically targeting NKCC1 and NKCC2. This compound also functions as an antagonist of GABAA receptors, demonstrating a 100-fold selectivity for α6-containing receptors over α1-containing receptors. Furosemide sodium is utilized primarily as a loop diuretic and is valuable in research applications related to congestive heart failure, hypertension, and edema.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 41733-55-5 |
| Applications | NKCC Inhibitor |
| Formula | C12H10ClN2NaO5S |
| Molecular Weight | 352.73 |
| SMILES | O=C(C1=CC(S(=O)(N)=O)=C(C=C1NCC2=CC=CO2)Cl)O[Na] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.