Fig. 1 · Structure
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Fuzapladib potassium
LFA-1 Activation Inhibitor
Fuzapladib potassium is a potent inhibitor of leukocyte-function-associated antigen type 1 (LFA-1) activation, which plays a crucial role in leukocyte adhesion. Additionally, it serves as a phospholipase A2 (PLA2) inhibitor, further contributing to its anti-inflammatory properties. This compound is widely utilized in research to investigate mechanisms of inflammation and leukocyte trafficking, making it valuable for studies related to autoimmune diseases and other inflammatory conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 141284-74-4 |
| Applications | LFA-1 Activation Inhibitor |
| Formula | C15H20F3KN3O3S |
| Molecular Weight | 418.50 |
| Synonyms | IS-741 potassium |
| SMILES | O=C(C1CCCCC1)NC2=CC(C(F)(F)F)=CN=C2NS(=O)(CC)=O.[K] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.