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FXIa-IN-10

FXIa Inhibitor

FXIa-IN-10 is a potent inhibitor of activated factor XI (FXIa) with a binding affinity (Ki) of 0.17 nM. This compound exhibits good oral bioavailability, making it suitable for in vivo studies. FXIa-IN-10 is valuable for research focused on anticoagulation therapies and the modulation of coagulation pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2816108-08-2
Applications	FXIa Inhibitor
Formula	C₂₃H₁₈Cl₂F₃N₉O₂
Molecular Weight	580.35
SMILES	CN1N=NC=C1C2=CN([C@@H](C3=CC=C(C4=C(N5N=NC(Cl)=C5)C=CC(Cl)=C4F)C=[N+]3[O-])CCOC(F)F)N=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.