Fig. 1 · Structure

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FXIIIa-IN-1

FXIIIa Inhibitor

FXIIIa-IN-1 is a potent and selective inhibitor of Factor XIIIa (FXIIIa) with an IC50 value of 2.4 μM. It operates by competing with the Gln-donor protein substrate, specifically dimethylcasein, to inhibit FXIIIa activity. This compound shows potential for the development of novel and effective anticoagulants, making it a valuable tool for research in coagulation and anticoagulation mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 55909-92-7
Applications FXIIIa Inhibitor
Formula C26H25N5O19S6
Molecular Weight 903.89
SMILES
NC1=C2C(O)=C(/N=N/C3=CC=C(S(=O)(CCOS(=O)(O)=O)=O)C=C3)C(S(=O)(O)=O)=CC2=CC(S(=O)(O)=O)=C1/N=N/C4=CC=C(S(=O)(CCOS(=O)(O)=O)=O)C=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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