Fig. 1 · Structure
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G-631
Tankyrase Inhibitor
G-631 is a potent tankyrase (TNKS1/TNKS2) inhibitor that modulates the Wnt/β-catenin signaling pathway by stabilizing AXIN. This compound has demonstrated weak anti-tumor activity in preclinical models of colorectal cancer. G-631 is suitable for research applications focused on the mechanisms of cancer progression and the exploration of therapeutic strategies for colorectal cancer.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1507370-78-6 |
| Applications | Tankyrase Inhibitor |
| Formula | C19H22F2N6O3 |
| Molecular Weight | 420.41 |
| SMILES | O=C1N=C(N2CCN(CC2)C3=C(C=C(C=C3F)OCCOC)F)NC4=C1C=NN4C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.