Fig. 1 · Structure
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γ-Glutamylvaline
CaSR activator
γ-Glutamylvaline (γ-Glu-Val) is a potent activator of the calcium-sensing receptor (CaSR) with demonstrated anti-inflammatory properties. This compound effectively inhibits tumor necrosis factor-alpha (TNF-α)-induced production of proinflammatory cytokines and enhances the expression of Wnt5a. Research applications for γ-Glutamylvaline include investigations into calcium-sensing receptor pathways in adipocytes, particularly in 3T3-L1 mouse models, where it has been shown to mitigate low-grade chronic inflammation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 2746-34-1 |
| Applications | CaSR activator |
| Formula | C10H18N2O5 |
| Molecular Weight | 246.26 |
| Synonyms | γ-Glu-Val |
| SMILES | [C@H](NC(CC[C@@H](C(O)=O)N)=O)(C(C)C)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.