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γ3-MSH

Catalog No.: A61689
Melanocortin Receptor
γ3-MSH is a peptide derived from the N-terminal segment of pro-opiomelanocortin (POMC) that primarily targets melanocortin receptors. It is known to stimulate aldosterone secretion in human adrenal tumor cells in vitro, making it a valuable tool for research into adrenal function and pathophysiology. This compound can be utilized in studies aimed at understanding the regulatory mechanisms of hormone secretion and the role of melanocortin signaling in adrenal tumors.
γ3-MSH 72629-64-2 Melanocortin Receptor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionγ3-MSH is a peptide derived from the N-terminal segment of pro-opiomelanocortin (POMC) that primarily targets melanocortin receptors. It is known to stimulate aldosterone secretion in human adrenal tumor cells in vitro, making it a valuable tool for research into adrenal function and pathophysiology. This compound can be utilized in studies aimed at understanding the regulatory mechanisms of hormone secretion and the role of melanocortin signaling in adrenal tumors.
Product Information
Catalog NumA61689
FormulaC126H188N44O37S
Molecular Weight2943.18
CAS Number72629-64-2
SequenceTyr-Val-Met-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-Gly-Arg-Arg-Asn-Gly-Ser-Ser-Ser-Ser-Gly-Val-Gly-Gly-Ala-Ala-Gln
Sequence shorteningYVMGHFRWDRFGRRNGSSSSGVGGAAQ
SMILESC([C@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H](CC2=CN=CN2)NC(CNC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)N)=O)C(C)C)=O)CCSC)=O)=O)=O)=O)CCCNC(=N)N)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(NCC(N[C@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)C)=O)C)=O)=O)=O)[C@@H](C)C)=O)=O)CO)=O)CO)=O)CO)=O)CO)=O)=O)CC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)=O)CCCNC(=N)N)=O)CC(O)=O)=O)C=5C=6C(NC5)=CC=CC6
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GPCR/G Protein > Melanocortin Receptor