Fig. 1 · Structure
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G6Pase catalytic enzyme-IN-1
glucose-6-phosphatase catalytic enzyme Inhibitor
G6Pase catalytic enzyme-IN-1 is a competitive inhibitor of the glucose-6-phosphatase catalytic enzyme, demonstrating an IC50 of 10 μM in pig liver microsomes. This compound is crucial for investigations into the regulation of glucose metabolism and has significant implications for research on type 2 diabetes. Its role in inhibiting glucose-6-phosphatase makes it a valuable tool for studying metabolic pathways and therapeutic interventions in glucose homeostasis disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 237402-29-8 |
| Applications | glucose-6-phosphatase catalytic enzyme Inhibitor |
| Formula | C20H19N3 |
| Molecular Weight | 301.39 |
| SMILES | N=1C=CC=CC1C=NN(CC=2C=CC=CC2)CC=3C=CC=CC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.