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G7-18NATE

Grb7 Inhibitor

G7-18NATE is a peptide inhibitor targeting the Grb7 SH2 domain, exhibiting a binding affinity of 18.1 µM. This compound has demonstrated significant biological activity by inhibiting cell proliferation, motility, and invasion, as well as disrupting 3D culture formation in various cancer cell lines. G7-18NATE serves as a valuable tool for research focused on cancer biology and the role of Grb7 in tumor progression.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	936728-13-1
Applications	Grb7 Inhibitor
Formula	C₆₇H₈₀N₁₄O₁₉S
Molecular Weight	1417.50
SMILES	C(C=1C=2C(NC1)=CC=CC2)[C@H]3C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CC5=CC=C(O)C=C5)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@]([C@@H](C)O)(C(=O)N[C@@H](CC6=CC=CC=C6)C(=O)N7[C@](C(=O)N[C@H](C(N)=O)CSCC(=O)N3)(CCC7)[H])[H]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.