Fig. 1 · Structure
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GAC0001E5
LXR Inverse Agonist
GAC0001E5 is an inverse agonist of liver X receptors (LXR) that exhibits significant antiproliferative activity. This compound is relevant in cancer research, as it modulates lipid metabolism and cellular proliferation pathways. Its mechanism of action may provide insights into therapeutic strategies targeting LXR-related signaling in tumorigenesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inverse Agonist |
| CAS Number | 927969-67-3 |
| Applications | LXR Inverse Agonist |
| Formula | C17H12F3N3O |
| Molecular Weight | 331.29 |
| SMILES | O=C1N=C(NC(C2=CC=CC=C2)=C1)NC3=CC=CC(C(F)(F)F)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.