Galectin-3 antagonist 1 is a specific inhibitor of Galectin-3, exhibiting a Kd value of 5.3 μM. This compound also demonstrates binding affinities to other galectins, with Kd values of 250 μM for Gal-4N, 18 μM for Gal-4C, and 450 μM for Gal-8C. It serves as a valuable tool for investigating the role of Galectin-3 in various biological processes and its implications in disease states, making it suitable for research in cancer, inflammation, and fibrosis.
Galectin-3 antagonist 1 is a specific inhibitor of Galectin-3, exhibiting a Kd value of 5.3 μM. This compound also demonstrates binding affinities to other galectins, with Kd values of 250 μM for Gal-4N, 18 μM for Gal-4C, and 450 μM for Gal-8C. It serves as a valuable tool for investigating the role of Galectin-3 in various biological processes and its implications in disease states, making it suitable for research in cancer, inflammation, and fibrosis.
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