Fig. 1 · Structure
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GalNAc-NAG37 phosphoramidite
N-acetylgalactosamine (GalNAc) Derivative
GalNAc-NAG37 phosphoramidite is an N-acetylgalactosamine (GalNAc) derivative that serves as a ligand for the asialoglycoprotein receptor (ASGPR). This compound is instrumental in synthesizing GalNAc-siRNA, facilitating targeted oligonucleotide delivery in research applications. Its ability to selectively interact with ASGPR enhances its potential for use in therapeutic strategies and gene silencing studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 2199491-27-3 |
| Applications | N-acetylgalactosamine (GalNAc) Derivative |
| Formula | C80H127N10O37P |
| Molecular Weight | 1851.88 |
| SMILES | CC(O[C@@H]1[C@H]([C@@H](O[C@@H]([C@@H]1OC(C)=O)COC(C)=O)OCCOCCNC([C@H](CCC(N[C@H](C(NCCOCCO[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)COC(C)=O)OC(C)=O)OC(C)=O)NC(C)=O)=O)CCC(NCCOCCO[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)COC(C)=O)OC(C)=O)OC(C)=O)NC(C)=O)=O)=O)NC([C@@H]4CC[C@@H](CC4)OP(OCCC#N)N(C(C)C)C(C)C)=O)=O)NC(C)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.