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GalNAc-NAG37 phosphoramidite

Catalog No.: A89265
N-acetylgalactosamine (GalNAc) Derivative
GalNAc-NAG37 phosphoramidite is an N-acetylgalactosamine (GalNAc) derivative that serves as a ligand for the asialoglycoprotein receptor (ASGPR). This compound is instrumental in synthesizing GalNAc-siRNA, facilitating targeted oligonucleotide delivery in research applications. Its ability to selectively interact with ASGPR enhances its potential for use in therapeutic strategies and gene silencing studies.
GalNAc-NAG37 phosphoramidite 2199491-27-3 N-acetylgalactosamine (GalNAc) Derivative
Grouped product items
Size Price Stock Qty
50mg
$115.00
In stock
100mg
$175.00
In stock
500mg
$425.00
In stock
1g
$680.00
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGalNAc-NAG37 phosphoramidite is an N-acetylgalactosamine (GalNAc) derivative that serves as a ligand for the asialoglycoprotein receptor (ASGPR). This compound is instrumental in synthesizing GalNAc-siRNA, facilitating targeted oligonucleotide delivery in research applications. Its ability to selectively interact with ASGPR enhances its potential for use in therapeutic strategies and gene silencing studies.
Product Information
Catalog NumA89265
FormulaC80H127N10O37P
Molecular Weight1851.88
CAS Number2199491-27-3
SMILESCC(O[C@@H]1[C@H]([C@@H](O[C@@H]([C@@H]1OC(C)=O)COC(C)=O)OCCOCCNC([C@H](CCC(N[C@H](C(NCCOCCO[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)COC(C)=O)OC(C)=O)OC(C)=O)NC(C)=O)=O)CCC(NCCOCCO[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)COC(C)=O)OC(C)=O)OC(C)=O)NC(C)=O)=O)=O)NC([C@@H]4CC[C@@H](CC4)OP(OCCC#N)N(C(C)C)C(C)C)=O)=O)NC(C)=O)=O
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