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Ganetespib (STA-9090)

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Hsp90 inhibitor

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Catalog No. A11402

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Ganetespib 50mg A11402-50

Regular Price: $240.00

Special Price: $216.00

Ganetespib 100mg A11402-100

Regular Price: $440.00

Special Price: $396.00

Ganetespib 5mg A11402-5

Regular Price: $70.00

Special Price: $63.00

Ganetespib 10mg A11402-10

Regular Price: $100.00

Special Price: $90.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Ganetespib is a potent, synthetic, small molecule inhibitor of Hsp90, a chaperone protein that is essential to the function of certain other proteins that drive the growth, proliferation, and survival of many different types of cancer.

Ganetespib (STA-9090)

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Publications citing Adooq Products
Ganetespib (STA-9090) Citations (2)
  • Yamada-Kanazawa S,et al. Inhibition of heat shock protein 90 exerts an antitumour effect in angiosarcoma: involvement of the vascular endothelial growth factor signalling pathway, Br J Dermatol, 2017, Aug;177(2):456-469 28078663
  • Hiroki Murano,et al. A purine-type heat shock protein 90 inhibitor promotes the heat shock response in Arabidopsis, Plant Biotechnol Rep, 2017, 11:107-113

Chemical Information

Catalog Num A11402
Actions Inhibitor
M. Wt 364.4
Formula C20H20N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 888216-25-9
Synonyms STA9090
SMILES code CC(C)C1=CC(=C2NNC(=O)N2C3=CC4=C(C=C3)N(C=C4)C)C(=O)C=C1O
Chemical Name 5-[2,4-dihydroxy-5-(1-methylethyl)phenyl]-4-(1-methyl-1H-indol-5-yl)-2,4-dihydro-3H- 1,2,4-triazol-3-one

Biological Activity

Description
Ganetespib is a potent, synthetic, small molecule inhibitor of Hsp90, a chaperone protein that is essential to the function of certain other proteins that drive the growth, proliferation, and survival of many different types of cancer.
Targets
HSP90 (OSA 8 cells)
4 nM

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.44 mL 137.21 mL 274.42mL
0.5 mM 5.49 mL 27.44 mL 54.88 mL
1 mM 2.74 mL 13.72 mL 27.44 mL
5 mM 0.55 mL 2.74 mL 5.49 mL

*The above data is based on the productmolecular weight 364.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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