Ganglioside GM2-d3 ammonium is a deuterium-labeled version of the sialylated glycosphingolipid Ganglioside GM2. This compound primarily targets the integrin β1 receptor, enhancing tumor cell migration and invasion through the activation of the FAK/Src/Erk-MAPK signaling pathway, which induces actin cytoskeleton remodeling. Due to its significant role as a human tumor antigen found in tumor cells and fetal brain tissue, Ganglioside GM2-d3 is valuable for research applications focused on cancer biology and neurodegenerative disorders, allowing for the study of pathological processes associated with its abnormal expression and accumulation.
Ganglioside GM2-d3 ammonium is a deuterium-labeled version of the sialylated glycosphingolipid Ganglioside GM2. This compound primarily targets the integrin β1 receptor, enhancing tumor cell migration and invasion through the activation of the FAK/Src/Erk-MAPK signaling pathway, which induces actin cytoskeleton remodeling. Due to its significant role as a human tumor antigen found in tumor cells and fetal brain tissue, Ganglioside GM2-d3 is valuable for research applications focused on cancer biology and neurodegenerative disorders, allowing for the study of pathological processes associated with its abnormal expression and accumulation.
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