Fig. 1 · Structure
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Ganoderenic acid B
Triterpene
Ganoderenic acid B is a lanostane-type triterpene derived from Ganoderma lucidum, primarily targeting ABCB1. This compound has demonstrated a significant ability to reverse multidrug resistance in HepG2/ADM cells against Doxorubicin. Its biological activity suggests potential applications in cancer research, particularly in overcoming drug resistance in chemotherapy.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 100665-41-6 |
| Applications | Triterpene |
| Formula | C30H42O7 |
| Molecular Weight | 514.65 |
| SMILES | CC1(C)[C@@H](O)CC[C@]2(C)C3=C([C@@]4(C(C[C@H]([C@]4(CC3=O)C)/C(C)=C/C(CC(C)C(O)=O)=O)=O)C)[C@@H](O)CC12 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.