Fig. 1 · Structure
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GCN2-IN-7
GCN2 Inhibitor
GCN2-IN-7 is a selective inhibitor of the general control nonderepressible 2 (GCN2) with an IC50 of 5 nM. This compound is known for its ability to modulate cellular stress responses, showcasing significant anti-tumor activity in vivo. It serves as a valuable tool for research into cancer biology and the role of GCN2 in tumorigenesis and therapeutic resistance.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2396465-33-9 |
| Applications | GCN2 Inhibitor |
| Formula | C22H23BrN8OS |
| Molecular Weight | 527.44 |
| SMILES | O=C([C@@]1(C)C[C@H](NC2=NC=C3C(N(C4=CC=C(C5=NN=C(C)S5)C=C4)N=C3Br)=N2)CC1)NC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.