Fig. 1 · Structure

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GD3 Ganglioside

Mitochondrial Permeability Inducer

GD3 Ganglioside is a critical ganglioside found in human melanoma that acts as a mitochondrial permeability inducer. It directly targets mitochondria in a Bcl-2-controlled manner, facilitating the release of pro-apoptotic factors. GD3 ganglioside is synthesized rapidly from ceramide following the clustering of death-inducing receptors, thereby triggering apoptotic pathways. This compound is valuable for research into apoptosis and mitochondrial function in cancer studies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inducer
CAS Number 62010-37-1
Applications Mitochondrial Permeability Inducer
Formula C70H123N3Na2O29
Molecular Weight 1516.726

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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