GDC-0326
Catalog No.: A20437
PI3Kα inhibitor
GDC-0326 is a potent and selective PI3Kα inhibitor with a Ki of 0.2 nM.
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Biological Activity
| Description | GDC-0326 is a potent and selective PI3Kα inhibitor with a Ki of 0.2 nM. | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A20437 |
|---|---|
| Formula | C19H22N6O3 |
| Molecular Weight | 382.42 |
| CAS Number | 1282514-88-8 |
| SMILES | C[C@H](OC1=CC=C2C3=NC(C4=NC=NN4C(C)C)=CN3CCOC2=C1)C(N)=O |
| Synonyms | GDC0326, GDC 0326 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 72 mg/mL (188.27 mM) | |
| Water | Insoluble | ||
| Ethanol | 18 mg/mL (47.07 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.15 mL | 130.75 mL | 261.49 mL |
| 0.5 mM | 5.23 mL | 26.15 mL | 52.3 mL |
| 1 mM | 2.61 mL | 13.07 mL | 26.15 mL |
| 5 mM | 0.52 mL | 2.61 mL | 5.23 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
