GDC-0575 (ARRY-575, RG7741)

Catalog No.: A16811
Chk1 inhibitor
GDC-0575 (ARRY-575, RG7741) is a potent and selective CHK1 inhibitor with an IC50 of 1.2?nM.
Grouped product items
Product Name Price Stock Qty
GDC-0575 (ARRY-575, RG7741) 5mg
$180.00
In stock
GDC-0575 (ARRY-575, RG7741) 10mg
$280.00
In stock
GDC-0575 (ARRY-575, RG7741) 50mg
$720.00
In stock
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Biological Activity
Discription GDC-0575 (ARRY-575, RG7741) is a potent and selective CHK1 inhibitor with an IC50 of 1.2?nM.
Product Information
Catalog Num A16811
Formula C16H20BrN5O
Molecular Weight 378.27
CAS Number 1196541-47-5
SMILES O=C(C1CC1)NC2=CNC3=NC=C(Br)C(N4C[C@H](N)CCC4)=C32
Synonyms GDC-0575; GDC 0575; GDC0575; ARRY-575; ARRY-575; ARRY575; RG7741; RG-7741; RG 7741; AK 687476; AK-687476; AK687476;
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 68 mg/mL (179.76 mM)
Water Insoluble
Ethanol 5 mg/mL (13.21 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.44 mL 132.18 mL 264.36 mL
0.5 mM 5.29 mL 26.44 mL 52.87 mL
1 mM 2.64 mL 13.22 mL 26.44 mL
5 mM 0.53 mL 2.64 mL 5.29 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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