GDC-0575 dihydrochloride

Catalog No.: A21567

CHK1 inhibitor

GDC-0575 dihydrochloride

GDC-0575 dihydrochloride Chemical Structure

CAS NO. 1657014-42-0

GDC-0575 dihydrochloride (ARRY-575 dihydrochloride) is an orally bioavailable CHK1 inhibitor, with an IC50 of 1.2 nM, and has antitumor activity.

Availability: In stock

Package Price Qty
5 mg
$189.00
10 mg
$326.00
50 mg
$966.00
100 mg
$1,932.00
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Biological Activity

GDC-0575 dihydrochloride (ARRY-575 dihydrochloride) is an orally bioavailable CHK1 inhibitor, with an IC50 of 1.2 nM, and has antitumor activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.16 mL 110.82 mL 221.64 mL
0.5 mM 4.43 mL 22.16 mL 44.33 mL
1 mM 2.22 mL 11.08 mL 22.16 mL
5 mM 0.44 mL 2.22 mL 4.43 mL

*The above data is based on the productmolecular weight 451.19. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21567
Actions Inhibitor
M. Wt 451.19
Formula C16H22BrCl2N5O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1657014-42-0
Synonyms ARRY-575 dihydrochloride, ARRY575, ARRY 575; RG7741 dihydrochloride, RG 7741, RG-7741, GDC0575, GDC 0575
SMILES O=C(C1CC1)NC2=CNC3=C2C(N4C[[email protected]](N)CCC4)=C(Br)C=C3.[H]Cl.[H]Cl

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