Fig. 1 · Structure
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Gemcitabine-13C,15N2 hydrochloride
Stable Isotope
Gemcitabine-13C,15N2 hydrochloride is a stable isotope-labeled variant of Gemcitabine hydrochloride, a pyrimidine nucleoside analog and antimetabolite. It primarily targets DNA synthesis and repair, effectively inducing autophagy and apoptosis in cancer cells. This reagent is utilized in chemical research to study metabolic pathways and biomolecular processes associated with gemcitabine and its pharmacological effects.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2757566-59-7 |
| Applications | Stable Isotope |
| Formula | C813CH12ClF2N15N2O4 |
| Molecular Weight | 302.64 |
| Synonyms | LY 188011-13C,15N2 hydrochloride |
| SMILES | OC[C@H]([C@@H](O)C1(F)F)O[C@H]1[15N]2C=CC(N)=[15N][13C]2=O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.