Fig. 1 · Structure
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Gemcitabine elaidate hydrochloride
Gemcitabine Prodrug
Gemcitabine elaidate hydrochloride is a lipophilic prodrug of Gemcitabine that targets tumor cells through metabolic conversion. This compound is readily hydrolyzed by esterases to release Gemcitabine, which can then be phosphorylated to exert its therapeutic effects. Gemcitabine elaidate hydrochloride demonstrates notable anti-tumor activity, making it a valuable reagent for cancer research and drug development applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2918768-08-6 |
| Applications | Gemcitabine Prodrug |
| Formula | C27H44ClF2N3O5 |
| Molecular Weight | 564.11 |
| Synonyms | CP-4126 hydrochloride; CO-101 hydrochloride; Gemcitabine 5'-elaidate hydrochloride |
| SMILES | O[C@@H](C(F)(F)[C@H](N1C(N=C(C=C1)N)=O)O2)[C@H]2COC(CCCCCCC/C=C/CCCCCCCC)=O.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.