Fig. 1 · Structure
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Gemcitabine monophosphate
Anticancer Agent
Gemcitabine monophosphate is an active intermediate of the nucleoside analog gemcitabine, primarily targeting DNA synthesis and repair mechanisms. It exhibits potent anticancer activity through its incorporation into DNA, resulting in cytotoxic effects that hinder tumor cell proliferation. This compound is being explored for its potential in targeted drug delivery systems, such as nanoparticles, enhancing its therapeutic efficacy in cancer treatment.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 116371-67-6 |
| Applications | Anticancer Agent |
| Formula | C9H12F2N3O7P |
| Molecular Weight | 343.18 |
| Synonyms | Gemcitabine 5′-phosphate |
| SMILES | OP(OC[C@@H]1[C@@H](O)C(F)(F)[C@H](N2C=CC(N)=NC2=O)O1)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.