Fig. 1 · Structure

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Gemfibrozil 1-O-β-glucuronide-d6

Stable Isotope

Gemfibrozil 1-O-β-glucuronide-d6 is the deuterated form of Gemfibrozil 1-O-β-glucuronide, known for its role as a powerful and competitive inhibitor of the cytochrome P450 isoform CYP2C8, with an IC50 value of 4.07 μM. This metabolite is essential for studying the pharmacokinetics and metabolism of Gemfibrozil, providing insight into its therapeutic mechanisms and potential interactions. Research applications include drug metabolism studies and the investigation of metabolic pathways in pharmacology.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1703747-47-0
Applications Stable Isotope
Formula C21H24D6O9
Molecular Weight 432.49
SMILES
CC(C=CC(C)=C1)=C1OCCCC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C(O[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)C(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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