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Gemfibrozil-d6-1

Cytochrome P450 Inhibitor

Gemfibrozil-d6-1 is a deuterated form of Gemfibrozil, a lipid-lowering agent primarily targeting peroxisome proliferator-activated receptor alpha (PPAR-α). This compound functions as a nonselective inhibitor of various cytochrome P450 isoforms, demonstrating inhibition constants (Ki) of 5.8 μM for CYP2C9, 24 μM for CYP2C19, 69 μM for CYP2C8, and 82 μM for CYP1A2. Gemfibrozil-d6-1 is valuable for studies investigating lipid metabolism and drug interactions involving P450 enzyme modulation.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1160569-36-7
Applications	Cytochrome P450 Inhibitor
Formula	C₁₅H₁₆D₆O₃
Molecular Weight	256.37
Synonyms	CI-719-d6-1
SMILES	O=C(C(C)(CCCOC1=CC(C([2H])([2H])[2H])=CC=C1C([2H])([2H])[2H])C)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.