Fig. 1 · Structure
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Gemfibrozil-d6
Stable Isotope
Gemfibrozil-d6 is a stable isotope-labeled derivative of Gemfibrozil, primarily known as a PPAR-α activator. This lipid-lowering agent also serves as a nonselective inhibitor of various cytochrome P450 isoforms, exhibiting Ki values of 5.8 μM for CYP2C9, 24 μM for CYP2C19, 69 μM for CYP2C8, and 82 μM for CYP1A2. It is useful in metabolic studies and drug interaction research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1184986-45-5 |
| Applications | Stable Isotope |
| Formula | C15H16D6O3 |
| Molecular Weight | 256.37 |
| Synonyms | CI-719-d6 |
| SMILES | OC(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])CCCOC1=C(C=CC(C)=C1)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.