Fig. 1 · Structure
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Gentisein
5-HT Uptake Inhibition
Gentisein (NSC 329491) is a potent inhibitor of serotonin uptake, demonstrating significant biological activity with an IC50 value of 4.7 µM. This compound serves as a valuable tool in neuropharmacological research, particularly in studies exploring serotonin-related pathways and their implications in mood disorders and neurobiology. Its role as a major metabolite of Mangiferin further emphasizes its relevance in investigations into natural product-derived pharmacological effects.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 529-49-7 |
| Applications | 5-HT Uptake Inhibition |
| Formula | C13H8O5 |
| Molecular Weight | 244.20 |
| Synonyms | NSC 329491; 1,3,7-Trihydroxyxanthone |
| SMILES | O=C1C2=C(C=C(C=C2O)O)OC3=C1C=C(C=C3)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.