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|Storage||at -20°C 3 years Powder|
|Synonyms||GGTI2418, GGTI 2418|
|SMILES code||CC1=C(N=CN1)CN2CCN([[email protected]](C2=O)CC3=CC=CC=C3)C(=O)N[[email protected]@H](CC(C)C)C(=O)O|
|Chemical Name||(S)-2-((S)-2-benzyl-4-((4-methyl-1H-imidazol-5-yl)methyl)-3-oxopiperazine-1-carboxamido)-4-methylpentanoic acid.|
|GGTI-2418 is a synthetic peptidomimetic inhibitor of geranylgeranyltransferase I (GGTase I) that appears to induce apoptosis by downregulating several pivotal oncogenic and tumor survival pathways.|
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||22.65 mL||113.25 mL||226.49mL|
|0.5 mM||4.53 mL||22.65 mL||45.3 mL|
|1 mM||2.26 mL||11.32 mL||22.65 mL|
|5 mM||0.45 mL||2.26 mL||4.53 mL|
*The above data is based on the productmolecular weight 441.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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