Fig. 1 · Structure
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Gimeracil-13C3
Stable Isotope
Gimeracil-13C3 is a stable isotope-labeled form of Gimeracil, designed to facilitate advanced metabolic studies. As a key component of the oral fluoropyrimidine derivative S-1, Gimeracil inhibits DNA double-strand break repair and acts as a potent inhibitor of dihydropyrimidine dehydrogenase (DPD). This reagent can be utilized in research applications related to cancer therapeutics and molecular pharmacology, providing insights into the metabolic pathways of fluoropyrimidines.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1184979-29-0 |
| Applications | Stable Isotope |
| Formula | C213C3H4ClNO2 |
| Molecular Weight | 148.52 |
| Synonyms | Gimestat-13C3 |
| SMILES | O=C1C=[13C](O)[13C](Cl)=[13CH]N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.