Fig. 1 · Structure
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Ginkgolic acid C17:1
Antitumor Agent
Ginkgolic acid C17:1 is a potent inhibitor of fatty acid synthase (FAS), exhibiting an IC50 of 10.5 µM. This compound demonstrates significant antitumor activity by inhibiting STAT3 phosphorylation and promoting apoptotic processes. Additionally, Ginkgolic acid C17:1 effectively disrupts the interaction between S-RBD and ACE2, showing promise against SARS-CoV-2-S pseudovirus. Furthermore, it has been shown to inhibit biofilm formation in pathogenic strains of enterohemorrhagic Escherichia coli and Staphylococcus aureus, underscoring its potential in antimicrobial research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 111047-30-4 |
| Applications | Antitumor Agent |
| Formula | C24H38O3 |
| Molecular Weight | 374.56 |
| SMILES | O=C(O)C1=C(O)C=CC=C1CCCCCCCCC/C=C\CCCCCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.