Fig. 1 · Structure
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Ginsenoside C-K hexapropionate ester
LXRα Agonist
Ginsenoside C-K hexapropionate ester is a selective agonist of LXRα, demonstrating minimal activation of LXRβ. This compound effectively upregulates the expression of downstream genes, such as ABCA1, thereby enhancing reverse cholesterol transport and alleviating lipid accumulation in macrophage-derived foam cells. It is primarily utilized in the study of atherosclerosis and its underlying mechanisms. Ginsenoside C-K hexapropionate ester is a synthetic derivative of ginsenoside Compound K, derived from Panax notoginseng saponins through modification with propionic anhydride.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 2861254-89-7 |
| Applications | LXRα Agonist |
| Formula | C54H86O14 |
| Molecular Weight | 959.25 |
| SMILES | C[C@]12[C@@]([C@@H](C[C@@]3([H])[C@]2(CC[C@]4([H])[C@@]3(CC[C@@H](C4(C)C)OC(CC)=O)C)C)OC(CC)=O)([H])[C@@](CC1)([H])[C@@](CC/C=C(C)/C)(C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)COC(CC)=O)OC(CC)=O)OC(CC)=O)OC(CC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.